Die Deutsche Forschungsgemeinschaft (DFG) wird ab Anfang 2007 16 neue
Zum Programm SPP 1267 "Sphingolipide - Signale und Krankheit" wurde nun die
Ausschreibung veröffentlicht. Sie finden den AUsschreibungstext (in englischer
Sprache) am Ende dieser Nachricht.
Deadline für Proposals: 18. September 2006
Prof. Dr. Erich Gulbins,
Institut für Molekularbiologie, Universität Duisburg-Essen, Hufelandstrasse 55
tel: 0201-723-3118, fax: 0201-723-5974,
Dr. Stefan Lohwasser,
tel: 0228-885-2359, fax: 0228-885-2777,
Ausschreibungstext, DFG, 19. Mai 2006:
The Senate of the Deutsche Forschungsgemeinschaft (DFG, German Research
Foundation) has established the Priority Programme “Sphingolipids – Signal and
Disease“. The programme is designed to run for six years.
The aim of this programme is to study the physiology, biochemistry, pathology,
pharmacology, medical chemistry and the medical application of bioactive
sphingolipids and their derivatives. Sphingolipids are central to the spatial
and temporal organisation of cellular signalling molecules and are critically
involved in the regulation of cell death, proliferation, cellular
differentiation and the pathogenesis of many diseases. Hence, the programme
particularly intends to characterise the novel signalling mechanisms and the
receptor crosstalks that mediate cellular effects of ceramide,
ceramide-1-phosphate, sphingosine and sphingosine 1-phosphate, as well as their
derivatives. It will also serve to identify and analyse receptors and
signalling mechanisms involved in this mediation process. As far as the role of
sphingolipids in human diseases is concerned, it would be highly beneficial to
develop new lead compounds and drugs that manipulate these lipids and serve to
treat cardio-reno-vascular, neurodegenerative, neuro-psychiatric, inflammatory,
tumour and immunological disorders.
The present call is limited to proposals that translate basic scientific
knowledge about cellular regulation and functions of sphingolipids into novel
therapeutic strategies and regimens. However, all proposals should focus on the
study of the regulation and function of these lipids and their derivatives.
They should be hypothesis driven and provide proof of concepts and principles
at least as preliminary data. Exploratory and exclusively descriptive studies
will only be funded if they are combined with studies on the principle biology
or the biomedical application of sphingolipids. Collaboration with other
research groups and the creation of synergies are encouraged. Studies on other
phospholipids or eicosanoids or research on predominantly descriptive genomes
and proteomes are excluded from this call.
Selection will be based on the quality of the proposal and the preliminary
data. Applications by junior scientists are encouraged. Applicants must have a
solid, high-quality publication record on sphingolipid research and, depending
on the seniority of the principle investigator, an established record of
Proposals for an initial three-year funding period should be submitted on paper
in triplicate, including appendices (one original, two copies), and on CD-ROM.
The CD-ROM should include the proposal and all appendices (publications,
etc.), preferably as PDF (or RTF) files. Proposals must be written in English,
and the title and project summary should also be provided in German. Please
submit proposals, marked as “SPP 1267” and addressed to the attention of Dr.
Stefan Lohwasser, to the Deutsche Forschungsgemeinschaft, Kennedyallee 40,
53175 Bonn. The deadline for submission is 18 September 2006. For scientific
enquiries please contact the programme coordinator, Prof. Dr. Erich Gulbins,
Institut für Molekularbiologie, Universität Duisburg-Essen, Hufelandstrasse 55,
45122 Essen, tel: 0201-723-3118, fax: 0201-723-5974, e-mail:
erich.gulbins(at)uni-essen.de. For administrative enquiries please contact Dr.
Stefan Lohwasser, tel: 0228-885-2359, fax: 0228-885-2777, e-mail:
stefan.lohwasser(at)dfg.de, or Sabine Pichler, ph: 0228-885-2752, e-mail: